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In a new study led by Yale Cancer Center, researchers show the nucleoside transporter ENT2 may offer an unexpected path to circumventing the blood-brain barrier (BBB) and enabling targeted treatment of brain tumors with a cell-penetrating anti-DNA autoantibody. The study was published today online in the Journal of Clinical Investigation Insight. “These findings are very
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Researchers at MIT have developed a kirigami-style stent that can provide localized drug delivery through needle-like projections that pop out when the stent is extended. The ‘spines’ on the stent’s surface deliver drug-loaded microparticles into the surrounding tissue, allowing for sustained drug release for an extended period. The technology is well suited to administering drugs
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Video highlights of COVID-19 data trends as of June 15, 2021. Explore COVID-19 trends around the world with our in-depth data tracking: New cases and cumulative cases: https://coronavirus.jhu.edu/data/cumulative-cases Daily new cases, testing, and positivity ratio by U.S. state: https://coronavirus.jhu.edu/testing/tracker/overview New cases by country: https://coronavirus.jhu.edu/data/new-cases
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Latest Chronic Pain News MONDAY, June 14, 2021 (HealthDay News) Many patients who are prescribed opioids after surgery could get the same level of pain relief with non-opioid alternatives such as ibuprofen or acetaminophen without the risk of addiction, researchers say. “Opioids have been a routine part of postsurgical pain care for decades, but the
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In fighting the COVID-19 pandemic, it’s not just the vaccines that require complicated cold supply chains and refrigerated storage. Polymerase chain reaction (PCR) tests — often considered the “gold standard” of testing — also have enzymes and reagents that need to be frozen. Northwestern University researchers have discovered that commercially available PCR tests can withstand
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Boston Scientific recently announced a clinical trial of its AGENT drug coated balloon. The device is coated with paclitaxel, an anti-restenotic drug, and aims to deliver the medication to the affected vessel wall during a percutaneous procedure. Coronary in-stent restenosis (ISR) is caused by occlusive scar tissue that develops in the stented portion of a
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“Rapid Fire with Medical Packaging Trailblazers” on June 15 during Virtual Engineering Days will cover several pressing issues in medical device packaging. Rod Patch, senior director, package engineering and product labeling, Johnson & Johnson Vision, and Jennifer Benolken, CPPL, medical device and regulatory package engineering specialist with DuPont Tyvek Medical Packaging, will lead a panel
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Researchers at the University of California San Diego have developed a high-throughput technique for 3D bioprinting. Using the new technology, the researchers can very quickly print large numbers of custom tissue samples that are suitable for drug screenings. Their printing method can yield a 96-well plate with tissue samples in each well in as little
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Genome-wide association studies using genotyping microarrays have long been a critical tool in understanding how genetic variation impacts disease. The problem is, most of these studies are based on genetic markers from people of European descent predominately, with little global diversity. Underrepresentation of diverse populations in genomic analysis hinders the ability to fully understand disease cause
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Despite the increased demand for medical supplies during the COVID-19 pandemic, it has still been a challenging time for employees in the medical device and diagnostic industry. Respondents to MD+DI‘s annual salary survey shared their frustrations and uncertainties from the last year, along with reports of recovery. Explained a medtech product design engineering manager back in March
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USA Swimming, the national governing body for the sport of swimming in the United States, and BD (Becton, Dickinson and Company) have partnered to provide COVID-19 testing at USA Swimming events. Specifically, rapid antigen tests using the BD Veritor Plus System will be conducted at the U.S. Olympic Team Trials – Swimming as an additional safety measure beyond the polymerase chain
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Video highlights of COVID-19 data trends as of June 14, 2021. The following states did not update data on Sunday, resulting in reduced Case and Death counts: Alabama; Alaska; Connecticut; District of Columbia; Florida; Idaho; Indiana; Kansas; Louisiana; Michigan; Mississippi; Montana; Nebraska; Nevada; New Mexico; North Carolina; Oklahoma; Rhode Island; South Carolina; South Dakota; Tennessee;
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Surfaces with anionic block copolymers can inactivate different viruses within minutes by making the polymer-microbe interface very acidic. Such surfaces can continuously disinfect surfaces without the need for reapplication of disinfectant. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the coronavirus disease 2019 (COVID-19) pandemic, is mainly transmitted by airborne particles. However, 
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Despite an early coronavirus disease (COVID-19) response against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the Philippines continues to grapple with skyrocketing cases, which have reached over 1.3 million total cases as of June 15, 2021. Study: Early response to COVID-19 in the Philippines. Image Credit: aldarinho / Shutterstock.com Researchers at the College of
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