Around the World

Genetic alterations of the KRAS gene are some of the most common mutations in lung cancer patients, but unfortunately these patients have few effective treatment options. Drugs that target the G12C mutation in KRAS have shown some activity in lung cancer; however, alternative signaling pathways are often activated that bypass the KRAS inhibitor, resulting in
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Thought LeadersDr. Mahshid DehghanInvestigator, Nutrition Epidemiology ProgramMcMaster University In this interview, News-Medical speaks to Dr. Mahshid Dehghan about her latest research into diet, and how a diet high in carbohydrates could increase your risk of heart disease. What provoked your research into diets? Diet is one of the most important modifiable risk factors for cardiovascular
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Researchers in the UK have reported the protocol for a longitudinal study investigating the risk of adverse physical and mental health outcomes related to coronavirus disease 2019 (COVID-19) among healthcare workers from different ethnic groups. The study aims to address the emerging evidence and growing concerns that healthcare workers (HCWs) from ethnic minority groups appear
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A University of Texas at Arlington researcher has received an Office of Naval Research (ONR) grant to examine the mechanics of how blast-like events cause damage to the brain. Ashfaq Adnan, professor of mechanical and aerospace engineering, has received a three-year, $944,845 grant to study the potential link between blast-like trauma and cellular and tissue
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The past century or so has seen unprecedented technological, scientific, and sociological evolution worldwide. These have accompanied global shifts in people’s lifestyles and rapid changes in the environment, both natural and man-made. An unfavorable consequence of these alterations has been the increasing burden of cancer on human society. As the country with the largest population,
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IRS refers to the application of insecticide onto the interior walls of houses. The study, by the Wits Research Institute for Malaria (WRIM) and the London School of Hygiene and Tropical Medicine (LSHTM), was published in The Lancet on 25 February 2021. Targeted vs blanket indoor residual spraying Malaria still represents one of the world’s
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Researchers at the Lady Davis Institute (LDI) at the Jewish General Hospital have discovered that increased levels of the protein OAS1 are associated with reduced mortality and less severe disease requiring ventilation among patients with COVID-19. Using drugs that boost OAS1 levels could be explored to try to improve these outcomes. The findings are published
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Porvair Sciences Krystal™ Glass Bottom microplate with Schott D 263® M technology provides unmatched performance for whole-plate CCD imaging and laser detection applications Krystal™ Glass Bottom plates combine the advantageous optical properties of glass, low background and low birefringence, with the versatility of a microplate. Constructed in ultra-pure grade borosilicate glass – the new D
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A new comprehensive course incorporating an interdisciplinary approach to disaster preparedness shows promise for better equipping health professionals in responding to disasters. Medical staff and researchers from Tohoku University and Fukushima Medical University organized the program. The two universities are well equipped in disaster response and preparedness given their regions were at the epicenter of
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The new HK Series Differential Refractometer from Testa Analytical Solutions e.K sets a benchmark for precise determination of specific refractive index increment (dn/dc) – an important parameter for polymer and protein molecular weight determination using light scattering techniques. The specific refractive index increment (dn/dc) is one of the most underestimated parameters in material science. The
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A study recently conducted at the Jenner Institute, University of Oxford, UK, has investigated the significance of a transmembrane glycoprotein basigin, or CD147, as a host cell co-receptor required for the entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19). The findings reveal that recombinant human basigin
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A team of scientists from the United States recently investigated the mutational signatures in the receptor-binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein. The findings reveal that the frequency of L452R mutation in the spike region has increased since November 2020. The L452R mutation, which is predicted to increase
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